CORDIS Project
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This project investigates the physical basis of memory storage in the brain by focusing on synapses. It aims to identify specific synapses involved in memory recall and analyze their stability and functionality over time using advanced optogenetic techniques.
The nature of the physical substrate of memory – or engram – is probably one of the longest studied mysteries in neuroscience, and yet it still remains elusive.
In recent years, the search for the engram has gained new momentum due to the possibilities of optogenetic activation and silencing of specific neurons in the brain.
Recent studies suggest that the engram could be defined as the subset of neurons that is necessary and sufficient to cause recall of a specific memory when activated.
But wh…
UNIVERSITAETSKLINIKUM HAMBURG-EPPENDORF
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