CORDIS Project
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This project investigates long noncoding RNAs (lncRNAs) in mammalian genomes, focusing on their roles in gene regulation and biological processes. By developing new methodologies, it aims to understand how these RNA molecules influence gene expression and could lead to therapeutic applications for diseases linked to ge…
Tens of thousands of loci in mammalian genomes produce long RNAs that do not go on to produce functional proteins, and are collectively called long noncoding RNAs (lncRNAs). A growing number of these have been shown to be important in various biological processes and human diseases.
How lncRNA genes function and, specifically, how their production, maturation, or RNA products affect other gene regulatory processes remains poorly understood and is the focus of this proposal.
We will build on a ri…
WEIZMANN INSTITUTE OF SCIENCE
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