CORDIS Project
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This project investigates how actin-based contraction and specific proteins influence the formation of hepatocyte apical domains and bile canalicular networks in the liver. By using advanced imaging techniques and molecular biology methods, it aims to enhance understanding of liver regeneration and function, which is c…
Failure of liver functioning affects millions of people around the world.
Despite of this and its known ability to regenerate itself, surprisingly little is understood about the mechanisms guiding both liver regeneration and functioning. A key element in providing liver functionality is the presence of specific cells in the tissue, but also their correct arrangement there.
This distinct microarchitecture relies on the correct polarization of cells, e.g. the hepatocytes.
The hepatocyte polarizati…
MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV
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