CORDIS Project
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This project investigates the role of lipoteichoic acid in the growth and division of Gram-positive bacteria, specifically Listeria monocytogenes and Staphylococcus aureus. It aims to uncover the molecular mechanisms linking LTA synthesis to cell division and shape regulation, utilizing newly developed bacterial mutant…
This proposal aims to provide insight into the physiological function of lipoteichoic acid (LTA) in the two Gram-positive bacterial pathogens Listeria monocytogenes and Staphylococcus aureus. LTA is an essential component of the envelope in Gram-positive bacteria.
While the chemical structure of this polymer was elucidated several decades ago, the key genetic determinants for its synthesis have been identified only recently.
These genetic studies made it clear that LTA has a crucial function wit…
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