CORDIS Project
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This project investigates the interactions between lipoproteins and endothelial cells to understand their role in cardiovascular diseases. By studying these interactions in live models, it aims to uncover new mechanisms that could lead to therapeutic targets for conditions like atherosclerosis and thrombosis.
Cardiovascular diseases (CVDs) are the leading cause of death throughout the world.
Elevated Low Density Lipoprotein (LDL) is a well-known cardiovascular risk factor and endothelial (ECs)-lipoprotein (LIPs) interactions underlie the initiation and progression of atherogenesis, thrombosis and other CVDs.The endothelium is a monolayer of cells that segregates the vascular contents from adjacent tissues.
In spite of being continually exposed to LIPs, ECs were long thought of as inert barriers, thro…
WEIZMANN INSTITUTE OF SCIENCE
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