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The LipidAge project investigates the role of complex lipids, particularly bis(monoacylglycero)-phosphate, in aging and age-related diseases. By utilizing various model organisms and advanced lipid profiling techniques, the project aims to understand how lipid metabolism influences healthy aging and lysosomal functions…
Aging has long been considered a passive process that could not be reverted.
Fortunately, it is now clear from genetic and pharmacological intervention studies that aging is actively regulated and can be influenced to reduce the burden of age-related diseases, such as neurodegenerative and metabolic diseases.
Studies in various organisms established the importance of dysregulated lipids in the development of aging and age-related diseases.
It remains unclear, however, how complex lipids and lipi…
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