CORDIS Project
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This project investigates the relationship between myelin loss and network dysfunction in multiple sclerosis. Using advanced imaging techniques, it aims to identify biomarkers that can monitor disease activity and inform treatment strategies.
Multiple sclerosis (MS) is a diffuse inflammatory and neurodegenerative disease of the central nervous system.
Neuroinflammation destroys the myelin sheaths wrapped around the axons and may lead to axon degeneration.
Repair processes trigger re-myelinisation.
Myelin loss delays or blocks signal propagation along axons in white matter tracts, impairing neuronal integration within the affected brain network.
The exact relationship between the amount of axonal de- and re-myelination and the resulti…
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