CORDIS Project
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This project focuses on advancing techniques in structural biology, particularly through the integration of X-ray crystallography and cryo-electron microscopy. By improving data analysis methods, it aims to enhance the resolution of complex biological structures.
Proper understanding of the biological processes related to complex macromolecular entities depends on the detailed description of their 3D structures.
For 100 years X-Ray Crystallography has been the main player in revealing high resolution structures.
In the last decade, Bayesian statistics has yielded a breakthrough for solving challenging structures thanks to the integration of specialised error models essential to extract a weak signal from noisy data.
Developed on such statistical methods,…
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