CORDIS Project
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This project investigates channelrhodopsins, proteins that act as light-sensitive ion channels, to understand their structure and function. The research aims to elucidate the mechanisms of ion transport and channel activation through advanced simulations.
Channelrhodopsins are type-I rhodopsin proteins found in green algae that function as sensory photoreceptors and turn into ion channels under illumination.
Upon light absorbance, the retinal moiety induces a conformational change on the protein that opens a channel through which ions can pass.Neurons expressing channelrhodopsin-2 (ChR2) can be depolarized rapidly and reversibly by illumination, hence allowing control of the activation/inactivation of neurons in specific locations of the brain. F…
MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV
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