CORDIS Project
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This project focuses on creating photoactive metal complexes that can bind to DNA, enabling the development of sensors and tools for studying DNA interactions. The research aims to synthesize multifunctional probes that can detect DNA sequences and potentially cleave DNA, utilizing advanced photophysical techniques.
Photoactive mono- and oligonuclear transition metal complexes containing DNA intercalative ligands will be synthesized.
In the latter case, both homo- and heterometallic complexes will be synthesized.
The photophysical properties of the complexes will be exploited to produce a number of outcomes: prototypical sensors for DNA sequences and/or structures that will produce a luminescent output on DNA binding, tools for investigating DNA/substrate binding events and the photophysical/electronic prop…
THE UNIVERSITY OF SHEFFIELD
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