CORDIS Project
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This project aims to develop advanced experimental tools for studying receptor dynamics using photolysis and laser microscopy. It focuses on creating new neuroactive compounds that enable efficient photolysis for investigating glutamate receptor properties and network activity in brain neurons.
Progress in science requires the development of new or better experimental tools.
Photolysis has provided a way to study kinetics of ligand activated signaling in situ at inaccessible intracellular and extracellular receptors for three decades.
It can now be combined with laser microscopy to provide high resolution spatio-temporal kinetics of receptors in situ, for photo-stimulation or photo-inhibition to study dendritic integration and networks, or for studying compartmentalization and distribu…
Université Paris Descartes
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