CORDIS Project
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The project investigates complex learning and maladaptive behaviors in primates, focusing on the neural mechanisms in the amygdala and prefrontal cortex. By developing new behavioral models, it aims to enhance understanding of emotional responses and anxiety disorders.
Major advances were made in understanding circuits that underlie aversive emotional learning.
The majority gained by using classical associative models, mainly tone/context-shock conditioning.
Failure to extinguish the response or to discriminate from other safe stimuli (generalization), form two main animal models for human anxiety-disorders and post-traumatic-stress.
These simple yet powerful approaches enabled cutting-edge techniques in rodents to unveil amygdala circuitry and its connectivit…
WEIZMANN INSTITUTE OF SCIENCE
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