CORDIS Project
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This project investigates the role of RNA-binding proteins in the infection and reactivation of Kaposi’s sarcoma-associated herpesvirus. By employing advanced molecular biology techniques, it aims to identify cellular and viral RBPs that could lead to new antiviral strategies.
Kaposi’s sarcoma-associated herpesvirus (KSHV), an oncogenic human γ-herpesvirus, is the cause of Kaposi’s Sarcoma (KS), primary effusion lymphoma and multicentric Castleman's disease with no effective therapies.
Like other herpesviruses, KSHV has a latent cycle with limited gene expression and a lytic cycle with expression of most viral genes and production of infectious viral particles. RNA-binding proteins (RBP) play key roles in RNA biology, including expression, export, stability, processin…
MEDIZINISCHE HOCHSCHULE HANNOVER
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United Kingdom, Glasgow
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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