CORDIS Project
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This project investigates integrons, genetic elements that enhance bacterial adaptability and contribute to antibiotic resistance. By focusing on the superintegron in Vibrio cholerae, it aims to understand the role of these genetic platforms in bacterial evolution and antibiotic resistance mechanisms.
Integrons are genetic platforms that enhance bacterial evolvability through the acquisition and stockpiling of new genes encoded in mobile elements named cassettes.
They are found in the chromosomes of environmental bacteria but some have acquired mobility through their association to transposons and conjugative plasmids.
These mobile integrons (MI) caused the unexpected rise of multidrug resistance that is now a major threat to modern medicine, and are good proof of the adaptive power of integr…
UNIVERSIDAD COMPLUTENSE DE MADRID
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