CORDIS Project
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This project investigates the role of KRAB-containing zinc finger proteins in gene regulation and their impact on mammalian health. It focuses on understanding how these proteins influence gene expression in the lymphatic and liver systems.
This project aims at exploring the roles or KRAB/KAP1-mediated gene regulation in mammalian physiology and the possible impact of its dysfunctions on human health.
The proper control of gene expression is paramount to all biological events, and is orchestrated through a sophisticated balance of activating and repressing influences.
The mouse and human genomes contain around four hundred genes encoding KRAB-containing zinc finger proteins (KRAB-ZFPs), a family of tetrapod-restricted sequence-spec…
ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE
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