CORDIS Project
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This project aims to enhance early diagnosis and treatment of ovarian cancer by targeting specific enzymes known as Kallikrein-related peptidases (KLKs). By developing specialized probes and therapeutic agents, the project seeks to better understand KLK activity in cancer progression and explore their potential as biom…
Ovarian cancer (OvCa) is one of the most fatal female gynaecological malignancies, resulting in 180,000 deaths annually.
The majority of patients have metastatic disease at time of diagnosis, thus, early diagnosis of OvCa remains a challenge to our society.
In addition, the low survival rates over the past decades have remained largely unchanged, evidencing the need of new therapies for OvCa.
Kallikrein-related peptidases (KLKs) are a family of 14 serine proteases which form a cross activation n…
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