CORDIS Project
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This project investigates how specific enzymes ensure accurate chromosome segregation during cell division. By employing advanced biochemical and cell biological methods, it aims to reveal the mechanisms that prevent errors in chromosome positioning and division timing, which are essential for producing genetically ide…
Equal segregation of chromosomes during cell division is vital to all life.
Using a unique combination of cell biological and biochemical techniques, I will show how an essential set of enzymes promotes error-free chromosome segregation.
During each cell division, genetically identical daughter cells are generated by accurate partitioning of the duplicated chromosomes.
This relies on proper spatio-temporal execution of various highly dynamic processes.
The activity of a small group of enzymes is…
UNIVERSITAIR MEDISCH CENTRUM UTRECHT
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