CORDIS Project
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This project focuses on the molecular mechanisms of membrane fusion, particularly in the context of Herpes simplex virus-1 entry into host cells. It employs various advanced techniques to dissect the fusion process at a molecular level, aiming to enhance understanding of cell biology.
Membrane fusion is a basic cell biological process found in diverse pathways ranging from vesicle trafficking and cell division to viral host entry.
It is mediated by fusion proteins residing in the membrane.
The underlying molecular mechanisms are supposed to follow a common order of events, i.e. fusion through hemifusion.
Cell entry of Herpes simplex virus-1 (HSV-1) is enabled by glycoproteins residing on the viral envelope membrane.
In contrast to other viruses, this is accomplished by differ…
THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD
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