CORDIS Project
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This project investigates the relationship between chromosome alterations in cancer and species evolution using advanced imaging and genomic techniques. By studying two deer species with different chromosome configurations, the research aims to uncover how cells adapt to these changes, with implications for understandi…
Alterations in chromosome number and size are hallmarks of cancer, and yet they are also crucial for species evolution.
Recent insight on chromosome structure and segregation, together with significant advances in genomic sequencing, established previously underappreciated parallels between the mechanisms of karyotypic evolution during speciation and cancer.
Importantly, alterations in chromosome number and size pose significant challenges for the cell division machinery.
However, how dividing c…
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