CORDIS Project
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This project aims to improve drug design by developing strategies for selective protein inhibition using computational and experimental methods. It focuses on the cyclophilin protein family to enhance therapeutic opportunities.
The rapid identification of synthetic molecules that selectively inhibit some proteins among families of closely related proteins is one of the major unsolved problems of modern drug discovery.
If such ability was at hand, it would radically revise our definition of the ‘druggable’ genome.
The goal of this proposal is to expand the state-of-the art of rational drug design with a new strategy that combines cutting edge computational techniques with modern experimental biophysical methods.
We…
THE UNIVERSITY OF EDINBURGH
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