CORDIS Project
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This research examines how immune cells migrate through endothelial barriers, focusing on specific transporter genes that facilitate communication between invading and invaded cells. Using Drosophila as a model, the project aims to identify key genes and their roles in cellular invasion and immune responses.
The ability of cells to move invasively through the cellular junctions of the endothelial vasculature underlies the function of the immune system and the metastatic spread of cancer.
How the invading and the invaded cells communicate to synchronize their actions during this behavior remains unclear.
We are studying these questions using the developmental migration of Drosophila immune cells through an epithelial barrier.
We have identified many mutants required for this process in a prelimina…
INSTITUTE OF SCIENCE AND TECHNOLOGY AUSTRIA
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