CORDIS Project
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This project investigates the mechanisms behind the variability of genetic robustness in individuals, focusing on how inherited mutations affect different people and how this knowledge can be applied to target cancer cells. Using live imaging of C. elegans embryos, it aims to link gene expression variations to phenotyp…
Biological systems are robust to perturbations, with many genetic, stochastic and environmental challenges having no or little phenotypic consequence.
However, the extent of this robustness varies across individuals, for example the same mutation or treatment may only affect a subset of individuals.
The overall objective of this project is to understand the cellular and molecular mechanisms that confer this robustness and why it varies across individuals.We will address three specific question…
FUNDACIO CENTRE DE REGULACIO GENOMICA
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