CORDIS Project
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This project investigates the regulation and quality control of the secretory pathway, focusing on the role of specific proteins in activating TACE, an important enzyme for cell signaling. It aims to understand how these proteins respond to various stimuli and their impact on inflammation.
The ability to release signals from the cell surface is dependent on the correct functioning of the secretory pathway.
This proposal focuses on trafficking regulation and quality control within the secretory pathway by members of the rhomboid superfamily, and members of the Signal Peptide Peptidase-Like family (SPPL).The metalloprotease TACE (TNF alpha converting enzyme) is an important sheddase for cell surface proteins, including the proinflammatory cytokine TNF (tumour necrosis factor), and l…
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
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