CORDIS Project
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INVICTUS develops a micro-fluidic platform to enhance drug delivery across the Blood-Brain Barrier using cavitation bubbles. This innovative approach aims to reduce reliance on animal testing while improving the efficiency of drug development for central nervous system disorders.
Disorders of the central nervous system (CNS) contribute almost 800 billion euros in annual European healthcare costs.
New compounds, effective in animal models, hardly work in humans, mostly due to the inability to cross the Brain Blood Barrier (BBB).
In these conditions cost-effective tools to alter BBB and, more generally, endothelial layer permeability is desirable before proceeding to expensive and time-consuming animal studies. INVICTUS (IN VItro Cavitation Through UltraSound) originates w…
UNIVERSITA DEGLI STUDI DI ROMA LA SAPIENZA
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