CORDIS Project
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This project investigates the hormone erythroferrone, which regulates iron absorption and release in the body. By understanding its mechanisms, the research aims to develop new treatments for various types of anemia that current therapies cannot effectively address.
The existence of an “erythron-related regulator” that intensifies iron absorption and its release from stores to meet the requirements for red blood cells synthesis was proposed in the 1950s.
Delineating this mechanism is of high biomedical importance as the pathway could be targeted to develop novel treatments for iron-restricted anemias that are very frequent but for which current therapies are ineffective (e.g. infections, inflammatory bowel disease, cancer, or chronic kidney disease) and for…
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
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