CORDIS Project
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This project investigates how specific neuronal circuits form in the brain, particularly focusing on the integration of interneurons into cortical circuits. It aims to understand the mechanisms that guide this process, which is crucial for addressing various neurodevelopmental disorders.
Understanding how brain function emerges through the assembly of specific neuronal circuits is one of the main challenges in neuroscience.
In the cerebral cortex, excitatory glutamatergic pyramidal cells and inhibitory interneurons constitute the main cellular elements of neuronal circuits.
Interneuron deficits seem to underlie a variety of neurodevelopmental and psychiatric disorders in humans, but our current knowledge of the mechanisms controlling their precise integration into cortical circu…
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