CORDIS Project
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This project focuses on improving the absorption of poorly soluble drugs in the gastrointestinal tract. By developing a computational platform and experimental tools, it aims to understand how lipid nanostructures affect drug solubilization and to design more effective oral dosage forms.
My research program explores molecular interplay between drug, dosage form and the complex environment of the gastrointestinal tract (GIT).
Drug molecules currently being discovered to cure e.g. CNS diseases, cancer and the metabolic syndrome show poor water solubility and 70-90% of recently discovered drugs have too poor solubility to allow absorption from the GIT.
For such compounds the dosage form can significantly improve the absorption.
My long-term goal is to establish a computational plat…
UPPSALA UNIVERSITET
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