CORDIS Project
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This project investigates the role of the YAP protein in repairing the intestinal lining in inflammatory bowel diseases. By studying its activation and interactions, it aims to identify potential drug targets to enhance tissue regeneration.
Inflammatory bowel diseases (IBDs), such as ulcerative colitis and Crohn’s disease, are chronic and debilitating pathologies of the intestines that affect 2.5-3.0 million patients in Europe and impose an economic burden of approximately €5.0bn/year on European healthcare systems.
Currently, no curative therapies are available and standard of care is limited to palliative anti-inflammatory treatments that fail to promote healing of the intestinal lining.
Enhancing epithelial regeneration is likel…
KOBENHAVNS UNIVERSITET
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