CORDIS Project
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This project explores the mechanisms of synaptic plasticity in the brain, particularly focusing on inhibitory neurons. By mapping plasticity across various brain regions, it aims to understand how these processes influence cognition and behavior.
Memory encoding occurs by strengthening or weakening of synapses among principal neurons.
However, excitatory synapses on some inhibitory neurons in the hippocampus also exhibit use-dependent long-term potentiation and depression (LTP and LTD), with important consequences for network homeostasis and information processing.
This proposal addresses the following areas: 1.
Although the rules determining which forms of plasticity occur at which synapses are emerging in the hippocampus, relatively li…
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