CORDIS Project
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This project investigates how immune responses are coordinated across different tissues during helminth infections, focusing on two nematode parasites. By analyzing immune interactions, particularly between type-2 and type-17 responses, it aims to enhance understanding of systemic immunity and inform future immunizatio…
Complex multicellular organisms evolved to ensure that each tissue or organ responds appropriately to infectious challenge.
Achieving pathogen elimination whilst preventing excessive collateral damage often requires the coordination of opposing types of immune responses (such as type-2 and type-17) within particular tissues.
Reaching this equilibrium is even more complex when we consider pathogens that migrate across different organs.
The mechanisms orchestrating immune responses between tissues…
THE UNIVERSITY OF MANCHESTER
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