CORDIS Project
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This project investigates the genetic transformation process in plants, focusing on how a specific DNA segment integrates into the plant genome. It aims to understand the molecular mechanisms involved, particularly the role of double-strand breaks and intermediate DNA forms in this integration.
Plant genetic transformation is a fascinating process by which the Agrobacterium transforms its host by delivering a well-defined fraction of its own genome (designated transfer DNA or T-DNA) as a single-stranded (ss) DNA molecule (designated T-strand) into the host cell.
The T-DNA integrates into the host genome and is expressed there.
Many of the biological mechanisms that govern the transformation process remain poorly understood and our understanding of the mechanisms by which T-DNA molecule…
BEN-GURION UNIVERSITY OF THE NEGEV
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