CORDIS Project
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The INTEGRATE project focuses on developing advanced computational methods to model cancer cell signaling processes. By integrating large-scale biomedical data, it aims to improve the understanding of cancer dynamics, which can lead to better drug targeting and personalized treatment strategies.
Modern cancer therapeutics target signalling processes within the cancer cells and the interaction of cancer and immune cells. A comprehensive understanding of these signalling processes is therefore essential to identify drug targets, plan clinical trials, and to select suitable drugs, drug combinations and drug dosages for a specific patient.
Yet, most of the available mathematical models capture only a small number of molecular species and pathways, thereby ignoring important crosstalk and fe…
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