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The INTACt project aims to develop a tool for personalized melanoma therapy by identifying patient-specific neo-antigens. This innovative approach seeks to enhance treatment efficacy and reduce the burden of traditional therapies.
Melanoma is the most aggressive, treatment-resistant and lethal type of skin cancer.
Its increasing incidence worldwide emphasizes the need for new treatment strategies.
Major recent breakthroughs in melanoma therapy have highlighted the role of immune T cell-mediated responses against tumor cells, showing that immune-system recognition of neo-antigens on cancer cells serves as a distinctive immunological signature.
However, current strategies to identify neo-antigens are biased, costly and time…
WEIZMANN INSTITUTE OF SCIENCE
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