CORDIS Project
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The project investigates the role of neuroinflammation in diseases like stroke and epilepsy, focusing on the NLRP3 inflammasome and its regulation. It aims to develop new therapeutic strategies targeting the molecular mechanisms underlying these conditions.
Local sterile inflammation arise in many pathologic states, including several diseases of the nervous system as brain stroke, neurodegenerative diseases and epilepsy.
The persistent and de-regulated inflammatory response sustains these neurological pathologies worsening their prognosis.
Different molecular players, as NLRP3 and P2X7 have been shown to contribute to the progression of these illnesses triggering the release of IL-1β and recruiting cellular components of the immune response at the…
UNIVERSITA DEGLI STUDI DI FERRARA
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