CORDIS Project
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This project uses zebrafish to study the interplay between inflammation and autophagy in tuberculosis. It aims to understand how these processes affect disease progression and could inform new treatment strategies.
The increasing occurrence of multidrug-resistant Mycobacterium tuberculosis strains makes tuberculosis (TB) a key priority for infectious disease research.
Inflammation and autophagy are two fundamental processes critical to TB pathogenesis.
Accumulating evidence shows that TB disease is worsened by deregulation of the inflammatory response.
On the other hand, autophagy has recently emerged as a crucial host defence mechanism.
Autophagy counteracts the ability of mycobacteria to survive inside h…
UNIVERSITEIT LEIDEN
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