CORDIS Project
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This project investigates the role of neutrophils in breast cancer metastasis. By studying the interactions between neutrophils and tumor cells, it aims to identify pathways that could be targeted to inhibit metastasis, potentially leading to new therapeutic strategies.
Metastatic disease is still largely unexplored, poorly understood and incurable.
Accumulating evidence indicates that cells and mediators of the immune system can facilitate metastasis.
Neutrophil accumulation in cancer patients has been associated with metastasis formation.
In mouse tumor models, neutrophils have been reported to be pro- or anti- metastatic, but the underlying mechanisms involved in either function remain largely elusive.
This proposal outlines a research program aimed at resol…
STICHTING HET NEDERLANDS KANKER INSTITUUT-ANTONI VAN LEEUWENHOEK ZIEKENHUIS
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