CORDIS Project
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This project investigates the use of growth factors to stimulate lung development in fetuses with congenital diaphragmatic hernia. By exploring pharmacological treatments alongside existing prenatal procedures, the aim is to improve survival rates and health outcomes for affected newborns.
Pulmonary hypoplasia is a significant cause of perinatal death and occurs with an incidence of 15%. A common (1:2500 newborns) malformation resulting in hypoplastic lungs is congenital diaphragmatic hernia (CDH).
Affected lungs have reduced and functionally altered airways and vessels, leading to respiratory deficiency and pulmonary hypertension in the neonatal period.
Nowadays, prenatal fetoscopic endoluminal tracheal occlusion (FETO) can be offered in selected cases to prevent excess of pulmon…
MEDIZINISCHE UNIVERSITAT GRAZ
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