CORDIS Project
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This project focuses on developing a new laboratory system to study how microRNAs regulate gene expression, particularly the tumor-suppressor microRNA let-7. It aims to uncover the molecular mechanisms of gene silencing and identify the components involved in these processes, with potential applications in disease diag…
Over the past decade, micro (mi) RNAs have emerged as key regulators of gene expression.
Many miRNAs have been linked to diseases, such as cancer or diabetes.
MiRNAs bind to specific sequences in the 3’-untranslated region (UTR) of mRNAs, thereby causing inhibition of translation and/or mRNA degradation.
However, the detailed molecular mechanism and the factors involved in miRNA-mediated gene silencing are still incompletely understood.
The primary research objective of the current proposal is t…
EUROPEAN MOLECULAR BIOLOGY LABORATORY
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