CORDIS Project
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This project investigates the eukaryotic translation initiation factor 3 (eIF3) subunits to develop small molecules targeting cancer therapy. By utilizing computational modeling and experimental validation, it aims to understand the interactions of eIF3 subunits and their role in cancer progression.
Eukaryotic translation initiation is a process wherein ribosomal subunits are assembled by eukaryotic initiation factor (eIF) proteins.
Mammalian eukaryotic translation initiation factor 3 (eIF3), consisting of the 13 subunits eIF3a to eIF3m, is the largest and most complex eIF.
Due to the emerging understanding of the role of eIF3 in a wide range of cancers, there is an increasing interest to examine its many subunits as potential therapeutic targets.
Furthermore, interactions between subunit e…
UGOT - GOETEBORGS UNIVERSITET/UNIVERSITY OF GOTHENBURG
GOETEBORGS UNIVERSITET
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BUDAPEST UNIVERSITY OF TECHNOLOGY AND ECONOMICS
Hungary, Budapest
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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