CORDIS Project
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The IN-3D-CAN project focuses on developing advanced 3D models of human cardiac muscle to assess the cardiotoxicity of cancer treatments. By utilizing organ-on-chip technology, it aims to enhance drug screening processes and improve safety in cancer therapies.
Rationale:
Cardiotoxicity side effects are a recurrent problem for cancer therapies, fatally illustrated by the death of numerous patients treated with anthracycline chemotherapeutics.
More recently, cardiac complications have also been found for antibody-based and immunotherapy treatments.
Microphysiological systems and organs-on-chips may provide part of the long-term solution to these issues, by introducing improved means for studying human tissue in vitro.
Main objective:
The overarching obj…
TECHNICAL UNIVERSITY OF DENMARK DTU
DANMARKS TEKNISKE UNIVERSITET
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