CORDIS Project
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The IMPACT project investigates how diverse neuron types in the developing brain contribute to spontaneous electrical activity before birth. It focuses on identifying pacemaker neurons and their molecular characteristics, aiming to understand their role in early brain function and potential implications for perinatal d…
Spontaneous activity is a prominent feature of the immature brain.
Even before birth and in absence of stimuli, neurons organize in networks and spontaneously generate correlated activity.
While spontaneous dynamics in the cerebral cortex have long been overlooked and considered just as epiphenomena, recent clinical data on preterm infants and preclinical studies have spurred a renewed interest for this early electrical activity.
However, appreciation of the role of spontaneous activity during t…
HUMANITAS UNIVERSITY
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