CORDIS Project
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This project examines the molecular composition of the immunopeptidome, which presents peptides to immune cells. It aims to understand its role in immunity and identify potential vaccine candidates against tuberculosis using advanced proteomic techniques.
MHC class I-associated peptides are presented at the cell surface for scrutiny by CD8+ T lymphocytes and are collectively referred to as the immunopeptidome.
The immunopeptidome plays crucial roles in many processes including autoimmunity, cancer immunosurveillance and elimination of pathogen-infected cells.
Nevertheless, very little is known about the molecular composition and biogenesis of the immunopeptidome in health and disease.
Through a multidisciplinary effort, I will conduct both fundam…
EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH
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