CORDIS Project
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This project aims to enhance the delivery of cancer treatments by normalizing tumor blood vessels, which often hinder effective drug delivery. It combines immunotherapy with vascular normalization to improve treatment outcomes for solid tumors through advanced modeling and experimental validation.
Inefficient delivery of cellular and molecular medicines to solid tumors can reduce dramatically the efficacy of treatment and affect negatively patient’s survival.
This explains in large part why standard chemo- and immune-therapies often fail to treat specific cancer types, even though these therapies are potent enough to eradicate cancer cells.
Abnormalities in the structure of the tumor vasculature hinder tumor perfusion and as a result the systemic delivery of the medicines.
In many tumor t…
UNIVERSITY OF CYPRUS
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