CORDIS Project
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This project investigates the metabolic dysfunction of natural killer T cells in glioblastoma, a highly aggressive brain tumor. By understanding how the tumor microenvironment affects these immune cells, it aims to develop new strategies for enhancing immunotherapy effectiveness against cancer.
Glioblastoma (GBM) is one of the most aggressive and fatal types of tumours with one of the worse survival rates.
Although immunotherapy is a remarkable and fast-growing field on cancer treatment it still faces the challenge that solid tumours are very suppressive for immune cells.
This suppressive tumour microenvironment (TME) is known to affect immune cells in different ways, as through the expression of inhibitory ligands and cytokines.
Recently, it has been shown that lipids and other metabo…
THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD, OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN
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