CORDIS Project
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This project aims to enhance cancer immunotherapy by investigating the role of plasmacytoid dendritic cells in inducing anti-tumor immunity. It will develop a novel single-cell technology platform to analyze immune cell interactions and improve vaccine strategies.
Successful immunotherapy against cancer is the result of a multitude of cellular interactions within the immune system.
It is highly exciting how vaccination with small numbers of human plasmacytoid dendritic cells (pDCs) can induce anti-tumour immunity in metastatic cancer patients.
Remarkably, how pDCs, as an extremely rare subset of cells, can act as Swiss army knives to regulate the tight balance between tolerance and immunity: i.e. secrete massive amounts of type I IFNs, prime T cells and e…
TECHNISCHE UNIVERSITEIT EINDHOVEN
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