CORDIS Project
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This project investigates how immune cells in fruit flies access energy, focusing on trehalose as a key nutrient instead of glucose. By using genetic tools and metabolic approaches, the research aims to understand the role of trehalose in the immune response of Drosophila, highlighting a potential evolutionary adaptati…
The immune response is an energy demanding process and immune cells must have a privileged access to energy/nutrients.
While in mammalian system, this privileged access is achieved for example by insulin-independent glucose transporter, how is it achieved in insect is not known.
The host laboratory has obtained preliminary results suggesting that the privileged access of fruit fly immune cells to nutrients might be achieved by using trehalose instead of glucose.
It is known for a very long time…
JIHOCESKA UNIVERZITA V CESKYCH BUDEJOVICICH
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