CORDIS Project
Funding breakdown and partner intelligence are Premium
Sign in and upgrade to Premium for EU contribution totals, consortium analytics, OpenAlex research context, and AI summaries. · 0 consortium intelligence fields visible of 1
Start free • Cancel anytime • 14-day refund guarantee
This project investigates the role of T cells in the brain's immune response and their influence on neuronal behavior when exposed to enriched environments. It aims to develop a gene therapy to selectively deplete brain T cells and explore their role in neurodevelopmental disorders, potentially leading to new therapeut…
T cells are part of the adaptive immune response.
Breaking the dogma of the brain immune privilege I demonstrated the presence of T cells in the healthy brain.
In the mouse brain they regulate neuronal morphology and behavior.
Surprisingly, brain T cells respond and proliferate upon exposure to an enriched environment (EE), suggesting a connection between neural activity and brain T cells. EE involves motoric, sensory and social stimulation.
Exposure of rodents to EE increases neurogenesis, enh…
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
Similar projects, consortium collaboration history, frequent partners, and OpenAlex research context.
Guests see up to 5 EuroSciVoc fields.
Guests see up to 5 topics.
Guests see up to 5 keywords.
