CORDIS Project
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This project investigates the adaptive immune system in jawless vertebrates, specifically lampreys, using advanced genetic techniques. By analyzing T cell development and function, the research aims to uncover fundamental principles of vertebrate immunity that could inform treatments for immune-related diseases in huma…
About 500 million years ago, the two sister groups of vertebrates independently evolved alternative forms of adaptive immunity, representing a striking example of convergent evolution.
Whereas the components and functions of the immune system in jawed vertebrates (ranging from sharks to humans) are well characterized, much remains to be learned about adaptive immunity in jawless vertebrates (lampreys and hagfishes).
Up to now, progress in understanding immunity in jawless fishes was hampered by…
MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV
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