CORDIS Project
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The IMMUNAGENOMICS project investigates how genetic variation and aging influence the immune response in brain metastases from cancer. By studying the tumor immune microenvironment, the project aims to enhance personalized treatment strategies for patients suffering from this severe condition.
Cancer represents a critical public health issue, with 2.74 million new cases diagnosed in Europe in 2022.
Most cancer-related deaths are attributed to metastatic spread and it is estimated that 20-40% of all cancer patients will develop metastases to the brain (BrM), facing a dismal prognosis.
Novel immunotherapies have shown promising outcomes in BrM patients, although a substantial proportion remain unresponsive.
This reflects the heterogeneous nature of the tumor immune microenvironment (TIM…
LUXEMBOURG INSTITUTE OF HEALTH
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