CORDIS Project
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This project investigates the mechanisms of immunological memory in chronic immune-mediated diseases, focusing on the roles of plasma cells and T helper cells. It aims to understand how these memory cells interact with their environment and contribute to inflammation, ultimately seeking to develop targeted therapeutic…
Immunological memory provides immunity against recurrent pathogens, but also can induce and regulate immunopathology.
In chronic immune-mediated diseases, a ""pathogenic"" immunological memory probably is the essential driver of inflammation, refractory to physiological regulation and state-of-the-art therapeutic immunosuppression, and thus a challenge for the development of novel, curative therapeutic strategies.
Despite its relevance, immunological memory is poorly understood.
We recently disc…
DEUTSCHES RHEUMA FORSCHUNGSZENTRUMBERLIN
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